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Supreme Labs

Pharmacogenetics / PGX

Eliminate the guesswork…

Supreme Pharmacogenetics

You don't know what you don't know

Pharmacogenomics is the study of your unique genetic makeup and how it influences drug effectiveness in order to personalize a patient’s drug therapy. Currently, medications are prescribed based on the patient’s weight, height, gender, condition, and previous drug history resulting in trial and error.  

There are many pathways in our body that metabolize drugs and even a small variation in our genetics can contribute to an adverse drug reaction. These risks can be significantly minimized through Pharmacogenomic testing.   

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What we DO know…

Pharmacogenetic testing testing provides evidence-based, actionable data that creates a personalized perspective for clinicians. This will help healthcare providers tailor any treatment plans to patients' specific needs and provides insight into unexpected drug monitoring results. The advancement of genetic research has led the healthcare community to have a greater understanding and the importance of genetics in all disease states. As a result, this has created a much higher demand for pharmacogenetic testing.

Statistics on Adverse Drug Events:

check_circle82% of American adults take at least one medication and 29% take five or more. (CDC).

check_circleAdverse Drug Events (ADE) cause over 700,000 emergency department visits each year. (CDC).

check_circleNearly 120,000 patients each year need to be hospitalized for further treatment (CDC).

check_circleOver 100,000 people die each year due to adverse drug events (FDA).

check_circle4th leading cause of death, Ahead of pulmonary disease, diabetes, AIDS, pneumonia, accidents and automobile deaths (FDA).

check_circleADEs cause injuries or death in 1 of 5 hospital patients. (New England Journal of Medicine).

check_circle$3.5 billion is spent on extra medical costs dues to ADEs annually (CDC).

check_circle75% of the US population doesn’t metabolize medications “normally” (FDA)

check_circleApproximately 2.2 million adverse drug events occur annually in the U.S. (CDC)

check_circleThe FDA lists more than 100 drugs that have a Black box warning suggesting a PGX be performed prior to taking (FDA)

check_circle1/3 of all clinically significant drug interactions are caused by drug/gene interactions, not drug/drug interactions (CDC)

check_circleADVERSE DRUG EVENTS ARE PREVENTABLE

In the US there are over 2.2 Million severe drug reactions

EACH YEAR

 

SUPREME PGX - Comprehensive Gene List

CYP2C19

CYP2C9

CYP2D6

CYP3A4

CYP3A5

CYP2B6

CYP1A2

ANKK1

FACTOR II

FACTOR V

COMT

HTR2A

HTR2C

MTHFR

VKORC1

ADRA2A

APOE

SLCO1B1

ABCB1

UGT2B15

GRIK4

TPMT

TPMT

Supreme Medical Labs

Our ultimate goal is to improve health outcomes and to improve the quality of life for all patients.

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